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Lady doing disinfection with ULV500 hypochlorous acid

Hypochlorous Acid as an Effective Disinfectant Against COVID-19

As of May 17, 2020, approximately 4.7 million people have been infected by the novel coronavirus or the Coronavirus Disease 2019 (COVID-19). Also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID 19 infection causes a cytokine storm, severe pneumonia, multiple organ failure, and acute cardiac injury. Because of this, health practitioners must limit and control the spread of the virus among themselves and their patients. The U.S. Environmental Protection agency recommends hypochlorous acid as an effective disinfectant against COVID-19.

How is COVID-19 Spread?

COVID-19 can easily be transmitted between people through touch or via mouth and nose secretions. These include saliva, respiratory secretions or secretion droplets. When these infectious droplets get into the mouth, nose, or eyes, they can cause people to catch the disease. That is why it is necessary to observe physical distancing since close contact can spread the disease fast. Staying at least 1 meter away helps minimize contact with these droplets, along with cleaning hands frequently and covering the mouth when sneezing or coughing. Since you cannot always maintain physical distancing, wear a face mask or a fabric mask to protect yourself and others.

Using Disinfectants to Fight COVID-19

The US Environmental Protection Agency has listed recommended disinfectants effective against COVID-19, including hypochlorous acid (HOCl). As a disinfectant, HOCl works by changing the virus's protective protein coat, making it lose its structure and aggregates, forming clumps of proteins with other viruses. Carrying no electrical charge, hypochlorous acid can oxidize the virus in a matter of seconds. This lack of electrical charge also allows it to penetrate the protective wall around the virus more efficiently. HOCl has been shown to inactivate various viruses effectively, including coronaviruses, in less than a minute.

Hypochlorous Acid as an Effective Disinfectant Against COVID-19

What is Hypochlorous Acid?

HOCl is a naturally occurring substance in the human body and other mammals. Hypochlorous acid is produced by the immune system agents—neutrophils, eosinophils, mononuclear phagocytes, and B lymphocytes—in response to an injury or infection. HOCl is shown to be effective against a broad range of microorganisms. As a disinfectant, it is nontoxic, noncorrosive, and effective in various forms, and relatively inexpensive, making it an ideal option for any cleaning needs.

How to Make Hypochlorous Acid

To make hypochlorous acid, you need precise proportions of salt, water, and vinegar. Since it is pretty much simple chemistry, you can make hypochlorous acid onsite. For that, you will need 1 L of water, 1 g of non-iodized salt, and 1 teaspoon of vinegar. The system can make 50 to 200 ppm (1ppm = 1mg/L) depending on its use. It takes 8 minutes to complete the electrolyzed solution. The disinfectant efficacy of HOCl includes contact time, concentration, and method of application as determining factors. Sunlight largely determines the stability of the HOCl solution. The solution becomes less stable when exposed to UV radiation, sunlight, or contact with air or when the solution’s temperature goes above 25°C. To maintain the solution's stability, you must store it in a cool, dark place with minimal air contact.

Hypochlorous Acid as an Effective Disinfectant

Aerosol size and Disinfection

Individuals working in the dental and medical field are at risk of aerosolization, which is the dispersal of a substance (such as medicine or viral particles) in the form of an aerosol. Aerosols are particles less than 50 mm in diameter. Aerosols can stay in the air for an extended period before settling on environmental surfaces or entering the respiratory tract. Typically, the nose filters particles larger than 10 mm. The coronavirus, which is considered an ultrafine particle at <.1 mm can easily enter the bloodstream or target lungs. dental drilling produces high concentrations of small particles ultrasonic and sonic transmissions in nonsurgical procedures have highest particle transmission with microbes aerosolization up to ft. these last anywhere from minutes hours if improper air current is present.>Various Uses of Hypochlorous Acid Mouth wash. In animal studies, ingesting HOCl did not show abnormal findings in terms of visual inspections of the mouth, histopathologic tests, or surface enamel roughness measurements on the teeth. Ophthalmology. Washing the eyes with pure hypochlorous acid can significantly reduce bacterial load on the periocular skin. After 20 minutes, at 0.01% concentration, HOCl decreased staphylococci by 99.6% on 71 eyes. Biofilm. Compared to sodium hypochlorite and chlorhexidine, HOCl significantly lowers oral bacteria, and the oral tissues better tolerate it. It is also effective as a mouthwash and toothbrush disinfectant. Wound care. In a published scientific article, a study reported that an HOCl solution had a 12-second kill time for numerous viruses and bacteria in most cases, helped promote wound healing and cell proliferation, and did not harm current healthy cells. Hand sanitizing. At 100- to 200-ppm strengths, HOCl hand sanitizers are effective against bacteria and viruses. Surface application. HOCl cleaning and disinfection resulted in significantly lower bacterial counts than standard cleaning and disinfection in outpatient surgical centers. Spray or fogger HOCl application. Because the fogging process can change the disinfectant's physical and chemical properties, you must perform a pre-fogging adjustment on the concentration and pH of the solution. You can inactivate viruses on both vertical and horizontal surfaces with appropriate concentrations, making fogging an effective approach. Above 50ppm, HOCl solutions are viricidal. At 100 and 200 ppm, spraying HOCl solutions directly onto sheets containing the virus for 10 seconds results in immediate virus inactivation. 50-ppm requires 3 minutes contact time. Sprayers make smaller particles, so the solution can be suspended in the air for a longer period, increasing the chance of contact with pathogens and inactivating them.

Why Use Petra's ULV500

ULV500 is a professional surface cleaner that can effectively sanitize and disinfect any surface in your medical and dental offices. Although it is extremely powerful in eliminating pathogens, it is 100 percent safe for humans as it is safe, non-toxic, and all-natural. Unlike other chlorine-based solutions, hypochlorous acid doesn’t irritate the skin, eyes, or lungs. It’s nontoxic, noncorrosive, and environment-friendly. Here are some of the known benefits of using Petra ULV500 Professional Surface Cleaner (HOCl):
  • 80 times more powerful than bleach without the unwanted effects like skin irritation
  • Green, natural, and safe
  • Effectively penetrates surfaces for microscopic level of clean
  • Convenient with ready-to-use solution
  • Versatile cleaning power with effective odor elimination
  • Superior germ-killing ability while keeping children and families safe


The COVID-19 pandemic has caused massive health care disruption and has strained the world economy. With the current unavailability of effective antiviral drugs and vaccines, preventive measures are necessary. Hypochlorous acid is an effective disinfectant against COVID-19. It is an ideal disinfectant option since it is nontoxic, noncorrosive, and relatively inexpensive. HOCl is an effective disinfectant in various settings, such as homes and offices. Fogging with hypochlorous acid has shown viricidal activity against various bacteria and viruses. Thus, hypochlorous acid is an ideal disinfectant in oral-maxillofacial surgery (OMS) office and various settings. Combined with adequate personal protective equipment, screening and social-distancing techniques, hand washing, and high-volume evacuation suction, HOCl solutions can greatly help prevent the transmission of COVID-19.
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